How to interpret IgE results?

Having a IgE test result when investigating patients with suspected allergy opens up important new possibilities. Knowing a patient’s specific IgE antibody levels for an allergen to which they are sensitive increases the possibility of ranking how the different allergens affect their symptoms. Allergens found at low levels that today do not result in symptoms can nevertheless help predict future symptom development. Based on thousands of test results, the generic curve opposite indicates what an allergen-specific IgE antibody value can mean in relation to symptoms. Although a final diagnosis should always be based on the physicians’ overall picture of the situation, a general rule of thumb is that the higher the IgE antibody value, the greater the likelihood of symptoms appearing. Allergy is not a black and white ‘yes or no’ disease. Classifying patients as such is therefore an oversimplification and should be restricted only to the very first stages of an allergy investigation.


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